CAR-T & Beyond: Future Cell Based Immunotherapeutic Strategies

07 Sep 2023
15:30
Stream 2
SPONSORED BY
Stemmatters

15:30am Chair Introduction

Chairperson: Sven Kili, Principal, Sven Kili Consulting

 

15:35am Presentation: Natural Killer Cell Based Therapies: Lessons Learned

  • Cover autologous and allogeneic clinical trials performed
  • Discuss strategies around NK cell persistence and efficacy
  • Role of donor and patient selection algorithms

Evren Alici, Head of Cell and Gene Therapy Group, Department of Medicine, Karolinska Institutet

 

15:50am Presentation: From Vision to Reality: Stemmatters’ Role in Supporting Development and Manufacturing of an Innovative Cone Replacement Therapy for Central Vision Loss

Rui A. Sousa, Chief Executive Officer & Chairman, Stemmatters

 

16:05am Presentation: A Personal Vaccine Platform Technology for Cancer and Infectious Disease

  • Dendritic cell vaccines are being manufactured as therapeutic anti-cancer vaccines and as anti-viral vaccines using antigens from self-renewing autologous cancer cells, and immunogenic proteins.  
  • Promising data from cancer trials includes safety, induction of immune responses, tumor regressions, and increased progression free and overall survival  
  • Promising data from COVID-19 trials demonstrated fewer and lower-grade adverse events, and superior protection to mRNA vaccine technologies.

Hans S. Keirstead, Chairman & Chief Executive Officer, AIVITA Biomedical, Inc.

 

16:20am Presentation: Okulovision’s Cone Progenitor Cell Therapy for Central Vision Loss 

  • Cone progenitor cells (cpc) are a pure population of cells that only regenerate cones after subretinal injection, and mediate improved visual function in rodent models 
  • Cpc are highly proliferative, facilitating manufacture to clinical scale 
  • Okulovision plans its first clinical trial in patients with cone dystrophies, then advance to patients with macular degeneration.

Marie Csete, Chief Executive Officer, OkuloVision 

 

16:35pm Closing Panel with Q&A 

With all session participants 

 

Speakers

Sven Kili
Principal
Sven Kili Consulting
Evren Alici
Head of Cell and Gene Therapy Group, Department of Medicine
Karolinska Institutet
Rui A. Sousa
Chief Executive Officer & Chairman
Stemmatters
Hans S. Keirstead
Chairman & Chief Executive Officer
AIVITA Biomedical, Inc.
Marie Csete
Chief Executive Officer
OkuloVision